Isotonitazene is a novel synthetic opioid that has not yet been banned. But deaths are on the rise. A new, legal synthetic opioid as deadly as fentanyl has been implicated in scores of deaths in the U.S.
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Isotonitazene is a novel synthetic opioid that has not yet been banned. But deaths are on the rise. A new, legal synthetic opioid as deadly as fentanyl has been implicated in scores of deaths in the U.S.The appearance of isotonitazene in North America’s narcotic food chain seems to confirm fears that last year’s ban by China of the non-medical use, supply, and production of synthetic opioids such as fentanyl would fail to shut the door on the lab drugs fueling America’s opioid crisis.
Barry K. Logan, a leading international authority on forensic toxicology and chief scientist at forensic firm NMS labs, said his colleagues have identified isotonitazene—which has a potency equivalent to fentanyl—in samples from more than 200 deceased drug users in the midwest and northeast since August last year.“Isotonitazene is the most persistent and prevalent new opioid in the U.S.,” said Logan, adding that he is now seeing 40 to 50 isotonitazene-related deaths per month in the U.S. compared to about six per month last summer.
Logan said his team had identified only a dozen new opioid substances last year in the U.S., but that isotonitazene had swiftly made a name for itself. “Most new opioids we see once or twice, but isotonitazene is the one that’s taking off.”
It has also reached Canada. In March, isotonitazene was found in 1,900 fake pharmaceutical pills in Nova Scotia and Newfoundland. The drug has been pressed into tablets to resemble Dilaudid, or hydromorphone. Dilaudid is a much-desired, highly euphoric synthetic opioid similar to oxycodone, aka Oxycontin.
In April 2019, in a move designed to appease President Trump, China banned all possible variants of the deadly synthetic opiate fentanyl. Trump had complained bitterly over China’s perceived inaction on its fentanyl trade, and he threatened economic punishment in return.
But within months of the Chinese blanket ban in April 2019 on fentanyl and all its derivatives, chemists in Chinese labs plundered medical literature and drug patents and produced this new, legal series of drugs that are just as powerful as fentanyl: a family of drugs called benzimidazoles, of which isotonitazene is one.
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